Mouse tPA Genetically Deficient Kidney Lyophilized from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Organ is flash-frozen immediately upon removal, then lyophilized.
Product Details:
- Species:Mouse
- Antigen:tPA
- Format:Lyophilized
- Storage Conditions:2° to 8°C
- Strain:C57BL6/SJL
- Chromosome:8
- Gene:PLAT
- Genomic TargetExon 4
- Mutation:16 base pair deletion
- Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA.
This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies.
Mouse Model Details
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